Profile of John Gurdon and Shinya Yamanaka, 2012 Nobel Laureates in Medicine or Physiology

Nobel Laureates in Physiology or Medicine

The 2013 Nobel Prize in Physiology or Medicine was awarded to Thomas Südhof, James Rothman, and Randy Schekman for their pioneering studies of membrane vesicle trafficking. In systems as diverse as the human brain and baker’s yeast and with approaches from mouse genetics and electrophysiology to enzymology to powerful genetic screens, they have unraveled this process, illuminating basic cell bi...

Nobel Laureates in Medicine or Physiology: a biographical dictionary

Weale (London) is not the first to be fascinated by Leonardo da Vinci's notes and drawings concerning the eye, the brain, and vision; but as he totally neglects earlier theories and observations (and historical work as relevant as David C. Lindberg's), he is unable to give any valid historical assessment. Strangely enough, he attributes the first correct description of the inverted retinal imag...

The 2011 Nobel Prize Laureates in Physiology or Medicine.

The egg and the nucleus: a battle for supremacy (Nobel Lecture).

Sir John Gurdon and Professor Shinya Yamanaka were the recipients of the 2012 Nobel Prize for Physiology or Medicine. This Spotlight article is a commentary on the early nuclear transplant work in Xenopus, which was very important for the Nobel award in 2012, and the influence of this work on the reprogramming field.

Shinya Yamanaka (1962- )

Shinya Yamanaka [5] gained international prominence after publishing articles detailing the successful generation of induced pluripotent stem (iPS) cells, first in mice, then in humans [6]. Yamanaka induced somatic cells to act like human embryonic stem cells [7] (hESCs), allowing researchers to experiment with non-embryonic stem cells [7] with a similar capacity as hESCs. The research involvin...